cIAP2 (BIRC3) Mouse Monoclonal Antibody [Clone ID: 1F12-E5-G12]

Specifications

Product Data
Clone Name	1F12-E5-G12
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for BIRC3 antibody: purified recombinant human c-IAP2 protein fragments expressed in E.coli
Isotype	IgG1
Formulation	ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72 kDa
Gene Name	baculoviral IAP repeat containing 3
Database Link	NP_001156 Entrez Gene 330 Human UniProt ID Q13489
Background	This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases.The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione,a potent inducer of free radicals.It contains 3 baculovirus IAP repeats and a ring finger domain.Transcript variants encoding the same isoform have been identified. [provided by RefSeq,Aug 2011]
Synonyms	AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

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