c Fos (FOS) Mouse Monoclonal Antibody [Clone ID: 7D6-A9-D4]

Specifications

Product Data
Clone Name	7D6-A9-D4
Applications	WB
Recommend Dilution	WB: 1:500
Reactivity	Human, Rat, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for C-FOS antibody: purified recombinant human FOS protein fragments expressed in E.coli.
Isotype	IgG1
Formulation	Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62 kDa
Gene Name	Fos proto-oncogene, AP-1 transcription factor subunit
Database Link	NP_005243 Entrez Gene 314322 RatEntrez Gene 702077 MonkeyEntrez Gene 2353 Human UniProt ID P01100
Background	The Fos gene family consists of 4 members: FOS,FOSB,FOSL1,and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1 As such,the FOS proteins have been implicated as regulators of cell proliferation,differentiation, and transformation.In some cases,expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq,Jul 2008]
Synonyms	AP-1; C-FOS; p55
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

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