TFIIB (GTF2B) Mouse Monoclonal Antibody [Clone ID: 2F6-A3]

Specifications

Product Data
Clone Name	2F6-A3
Applications	WB
Recommend Dilution	WB: 1:500
Reactivity	Human, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for GTF2B antibody: purified recombinant human TFIIB protein fragments expressed in E.coli.
Isotype	IgG2b
Formulation	ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34 kDa
Gene Name	general transcription factor IIB
Database Link	NP_001505 Entrez Gene 229906 MouseEntrez Gene 2959 Human UniProt ID Q00403
Background	GTF2B is one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Synonyms	TF2B; TFIIB
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Basal transcription factors

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