STAT1 Mouse Monoclonal Antibody [Clone ID: 6C2-F7-D12]

Specifications

Product Data
Clone Name	6C2-F7-D12
Applications	IP, WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for STAT1 antibody: purified recombinant human STAT1 protein fragments expressed in E.coli
Isotype	IgG2a
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	91 kDa
Gene Name	signal transducer and activator of transcription 1
Database Link	NP_009330 Entrez Gene 693650 MonkeyEntrez Gene 6772 Human UniProt ID P42224
Background	The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein can be activated by various ligands including interferon-alpha,interferon-gamma,EGF,PDGF and IL6.This protein mediates the expression of a variety of genes,which is thought to be important for cell viability in response to different cell stimuli and pathogens.Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq,Jul 2008]
Synonyms	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

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