SWAP70 Mouse Monoclonal Antibody [Clone ID: 2E9-E8-E9]

Specifications

Product Data
Clone Name	2E9-E8-E9
Applications	IP, WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for SWAP70 antibody: purified recombinant human SWAP70 protein fragments expressed in E.coli.
Isotype	IgG2b
Formulation	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70 kDa
Gene Name	SWAP switching B-cell complex 70kDa subunit
Database Link	NP_055870 Entrez Gene 20947 MouseEntrez Gene 293410 RatEntrez Gene 23075 Human UniProt ID Q9UH65
Background	Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion
Synonyms	HSPC321; SWAP-70
Reference Data

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