FKBP25 (FKBP3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:100 ?? 1:200) ; Western blotting (1:500)
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-FKBP3 antibody: mouse FKBP3 (FK506 Binding Protein 3), using a KLH-conjugated synthetic peptide containing an amino acid sequence from the central part of the protein
Isotype	IgG
Concentration	lot specific
Purification	Whole antiserum from rabbit containing 0.05% azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	FK506 binding protein 3
Database Link	NP_002004 Entrez Gene 30795 Mouse UniProt ID Q00688
Background	FKBP3 (UniProtKB/Swiss-Prot entry Q00688) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It acts as a receptor for FK506 and rapamycin, two immunosuppressants which inhibit T-cell proliferation. FKBP3 localizes to the nucleus and interacts with the transcription factor YY1 and with histone deacetylases. Therefore, it may play a role in chromatin modification and be important for the regulation of transcription.
Synonyms	FKBP-3; FKBP-25; FKBP25; PPIase
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency

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