WDR5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (1:1,000)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-WDR5 antibody: human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein.
Isotype	IgG
Concentration	lot specific
Purification	Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	WD repeat domain 5
Database Link	NP_060058 Entrez Gene 11091 Human UniProt ID P61964
Background	WDR5 (UniProtKB/Swiss-Prot entry P61964) belongs to the family of WD repeat proteins which are involved in different cellular processes such as cell cycle progression, signal transduction, apoptosis, and gene regulation. It is a component of the Set1A and Set1B histone H3 methylation complexes. These complexes methylate lysine 4 of H3, thereby activating gene transcription. WDR5 interacts with H3 dimethyl K4, but not with tri or mono methylated H3K4.
Synonyms	BIG-3; CFAP89; SWD3
Reference Data
Protein Families	Druggable Genome

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