Dynamitin (DCTN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-p50 Dynamitin Antibody: A synthesized peptide derived from human p50 Dynamitin
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50 kDa
Gene Name	dynactin subunit 2
Database Link	NP_006391 Entrez Gene 69654 MouseEntrez Gene 299850 RatEntrez Gene 10540 Human UniProt ID Q13561
Background	dynactin 2 Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. Belongs to the dynactin subunit 2 family. Subunit of dynactin, a multiprotein complex associated with dynein. Interacts with BICD2 and CEP135. Interacts with MAPRE1.
Synonyms	DCTN50; DYNAMITIN; HEL-S-77; RBP50
Note	p50 Dynamitin antibody detects endogenous levels of total p50 Dynamitin
Reference Data
Protein Pathways	Huntington's disease

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