PFKFB2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-PFKFB2 Antibody: A synthesized peptide derived from human PFKFB2
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58 kDa
Gene Name	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Database Link	NP_006203 Entrez Gene 18640 MouseEntrez Gene 5208 Human UniProt ID O60825
Background	PFKFB2 a bifunctional heterodimeric enzyme involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. Regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle.
Synonyms	FBPase-2; PFK-2
Note	PFKFB2 antibody detects endogenous levels of total PFKFB2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Fructose and mannose metabolism

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