Fibroblast activation protein, alpha (FAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-FAP-1 Antibody: A synthesized peptide derived from human FAP-1
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	88 kDa
Gene Name	fibroblast activation protein alpha
Database Link	NP_004451 Entrez Gene 14089 MouseEntrez Gene 192203 RatEntrez Gene 2191 Human UniProt ID Q12884
Background	PTPN13 Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Interacts with TRIP6 and TNFRSF6 (Fas receptor) through its second PDZ domain. Interacts with the C-terminal SVP motif of NGFR through its third PDZ domain.
Synonyms	DPPIV; FAPA; SIMP
Note	FAP-1 Antibody detects endogenous levels of FAP-1
Reference Data
Protein Families	Druggable Genome, Protease, Transmembrane

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