Dynamin 1 (DNM1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Dynamin 1 Antibody: Peptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	100kd
Gene Name	dynamin 1
Database Link	NP_004399 Entrez Gene 13429 MouseEntrez Gene 140694 RatEntrez Gene 1759 Human UniProt ID Q05193
Background	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis "SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis."
Synonyms	DNM
Note	The antibody detects endogenous levels of total Dynamin 1 protein.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis, Fc gamma R-mediated phagocytosis

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