SIRT3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-SIRT3 antibody: A synthesized peptide derived from human SIRT3
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29 kDa
Gene Name	sirtuin 3
Database Link	NP_036371 Entrez Gene 64384 MouseEntrez Gene 293615 RatEntrez Gene 23410 Human UniProt ID Q9NTG7
Background	NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Synonyms	SIR2L3
Note	SIRT3 antibody detects endogenous levels of total SIRT3
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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