KIRREL 3 (KIRREL3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
Isotype	IgG
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	KIRREL3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 64, 84 kDa; Observed: 60 kDa
Gene Name	kin of IRRE like 3 (Drosophila)
Database Link	NP_115920 Entrez Gene 67703 MouseEntrez Gene 315546 RatEntrez Gene 84623 Human UniProt ID Q8IZU9
Background	KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).
Synonyms	KIRRE; MRD4; NEPH2; PRO4502
Reference Data
Protein Families	Transmembrane

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