SLC1A7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	SLC1A7 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLC1A7.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SLC1A7 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 17, 52, 62, 68 kDa; Observed: 52 kDa
Gene Name	solute carrier family 1 member 7
Database Link	NP_001274524 Entrez Gene 6512 Human UniProt ID O00341
Background	The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).
Synonyms	170A; DDX13; HLP; SKI2; SKI2W; SKIV2; SKIV2L1; THES2
Reference Data

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