HOPX Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	HOPX antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 12 kDa; Observed: 183 kDa
Gene Name	HOP homeobox
Database Link	NP_001138932 Entrez Gene 84525 Human UniProt ID Q9BPY8
Background	HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).
Synonyms	Lobe; PRAS40
Reference Data

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