STAT6 Rabbit Polyclonal Antibody
CAT＃: TA349221S
Rabbit Polyclonal Anti-STAT6 Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1280.00
Product images
CNY 300.00
CNY 1430.00
CNY 2900.00
CNY 6650.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Raji cells |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human STAT6 |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 94 kDa |
| Gene Name | signal transducer and activator of transcription 6 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
| Synonyms | D12S1644; IL-4-STAT; STAT6B; STAT6C |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
热销推荐
