G protein alpha 13 (GNA13) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: A172 and 293T cells, mouse kidney tissue, human testis and brain malignant glioma tissue IHC: 50-200 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human GNA13
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44 kDa
Gene Name	G protein subunit alpha 13
Database Link	NP_006563 Entrez Gene 14674 MouseEntrez Gene 303634 RatEntrez Gene 10672 Human UniProt ID Q14344
Background	Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13gene. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5. Interacts with HAX1. Interacts (when active) with PPP5C (via TPR repeats); activates PPP5C phosphatase activity and translocates PPP5C to the cell membrane.
Synonyms	G13
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Long-term depression, Regulation of actin cytoskeleton, Vascular smooth muscle contraction

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