Lysyl tRNA synthetase (KARS) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: K562, A549, HT-29, 293T, Hela and Jurkat cells IHC: 100-300 Positive control: Human brain Predicted cell location: Cytoplasm or Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human KARS
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	68 kDa
Gene Name	lysyl-tRNA synthetase
Database Link	NP_005539 Entrez Gene 85305 MouseEntrez Gene 292028 RatEntrez Gene 3735 Human UniProt ID Q15046
Background	Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	CMTRIB; DFNB89; KARS1; KARS2; KRS
Reference Data
Protein Pathways	Aminoacyl-tRNA biosynthesis

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