Lamin B Receptor (LBR) Rabbit Polyclonal Antibody
CAT＃: TA350128S
Rabbit Polyclonal Anti-LBR Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Human fetal brain tissue IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human LBR |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 71 kDa |
| Gene Name | lamin B receptor |
| Database Link | |
| Background | The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. |
| Synonyms | DHCR14B; LMN2R; PHA; TDRD18 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
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