PTPRN Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human PTPRN
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein tyrosine phosphatase, receptor type N
Database Link	NP_002837 Entrez Gene 19275 MouseEntrez Gene 116660 RatEntrez Gene 5798 Human UniProt ID Q16849
Background	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP.
Synonyms	IA-2; IA2; ICA512; PTP; R-PTP-N
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Type I diabetes mellitus

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