ORAI1 Rabbit Polyclonal Antibody
CAT#: TA350773S
Rabbit Polyclonal Anti-ORAI1 Antibody
Size: 100 ul
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CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Human ovarian cancer tissue lysate IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ORAI1 |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | ORAI calcium release-activated calcium modulator 1 |
| Database Link | |
| Background | The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). |
| Synonyms | CRACM1; IMD9; ORAT1; TAM2; TMEM142A |
| Reference Data | |
| Protein Families | Transmembrane |
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