Dicer (DICER1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human DICER1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dicer 1, ribonuclease III
Database Link	NP_803187 Entrez Gene 192119 MouseEntrez Gene 23405 Human UniProt ID Q9UPY3
Background	This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
Synonyms	DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
Reference Data
Protein Families	Druggable Genome

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