RRAS Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human chromaffin cells tumor tissue and NIH/3T3 cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human RRAS
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23 kDa
Gene Name	related RAS viral (r-ras) oncogene homolog
Database Link	NP_006261 Entrez Gene 361568 RatEntrez Gene 6237 Human UniProt ID P10301
Background	Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene. RRAS has been shown to interact with RASSF5, NCK1, Bcl-2, ARAF and RALGDS. Regulates the organization of the actin cytoskeleton. Interacts with PLCE1. Interacts (active GTP-bound form preferentially) with RGS14.
Synonyms	Oncogene RRAS; related RAS viral (r-ras) oncogene homolog
Reference Data
Protein Families	Druggable Genome
Protein Pathways	MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction

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