PKM2 (PKM) Rabbit Polyclonal Antibody
CAT#: TA351941S
Rabbit Polyclonal Anti-PKM Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
CNY 2900.00
CNY 6650.00
CNY 3080.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Jurkat, A549, hepg2 and NIH/3T3 cell IHC: 25-100 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PKM |
Isotype | IgG |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 58 kDa |
Gene Name | pyruvate kinase, muscle |
Database Link | |
Background | This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. |
Synonyms | CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glycolysis / Gluconeogenesis, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus |
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