Plastin L (LCP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the C-terminus of human L-plastin protein. This sequence is identical to rat, mouse and human origins.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~70 kDa
Gene Name	lymphocyte cytosolic protein 1
Database Link	NP_002289 Entrez Gene 18826 MouseEntrez Gene 306071 RatEntrez Gene 3936 Human UniProt ID P13796
Background	L-plastin is a protein normally found in leukocytes (white blood cells) only. In these cells L-plastin regulates cell movement by interacting with actins, a major cellular protein that directly controls cell movement. Normal breast epithelial cells do not have L-plastin. It only presents in breast carcinoma cells. Furthermore, the amount of L-plastin contained in the cells correlates with the degree of invasiveness of these cells. Therefore, it appears that L-plastin may be important for the motility of breast cancer cells.
Synonyms	CP64; HEL-S-37; L-PLASTIN; LC64P; LPL; PLS2
Reference Data

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