FUT4 Mouse Monoclonal Antibody

Specifications

Product Data
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The human myelomonocytic leukemia cells.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59 kDa
Gene Name	fucosyltransferase 4
Database Link	NP_002024 Entrez Gene 2526 Human UniProt ID P22083
Background	CD15 is an antigen present on myelomonocytic cells and Lacto-Nfucopentose III (also known as hapten X). It is present on greater than 90% of granulocytes including neutrophils and eosinophils, and to a lesser degree, on monocytes. CD15 is expressed in Reed-Sternberg cells of Hodgkin’s disease (of the nodular sclerosis, mixed cellularity and lymphocyte-depleted subtypes). This antibody recognizes myeloid cells, mainly granulocytes but not on B cells, T cells, monocytes, erythrocytes or platelets. Positive staining for CD15 combined with a negative reaction for lymphocytic markers may provide support for Hodgkin’s disease. Fifty percent or more of adenocarcinomas have been described as showing significant cytoplasmic positivity for CD15. It does not detect most mesotheliomas.
Synonyms	CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1
Reference Data
Protein Families	Transmembrane
Protein Pathways	Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.