FGFR3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	WB 0.1-1 µg/ml ELISA N/A IP 2-5 µg/ml IHC 1-5 µg/ml FC Not tested
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 14aa synthetic peptide derived from aa 359-372 of human FGFR-3 protein.
Isotype	IgG
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	120 kDa
Gene Name	fibroblast growth factor receptor 3
Database Link	NP_000133 Entrez Gene 2261 Human UniProt ID P22607
Background	The fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides that are potent physiological regulators of growth and differentiation for a wide variet of cells of mesodermal, ectodermal and endodermal origin. Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3 and FGFR-4.FGFRs are emembers of the tyrosine kinase family of growth factor receptors. FGFR-3 is widely expressed in many fetal and adult human and animal tissues.
Synonyms	ACH; CD333; CEK2; HSFGFR3EX; JTK4
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Bladder cancer, Endocytosis, MAPK signaling pathway, Pathways in cancer, Regulation of actin cytoskeleton

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