C9orf72 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1-2µg/mL.IHC: 10µg/ml.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.
Isotype	IgG
Formulation	ALSFTD Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	ALSFTD Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 53 kDa; Observed: 52 kDa
Gene Name	chromosome 9 open reading frame 72
Database Link	NP_060795 Entrez Gene 203228 Human UniProt ID Q96LT7
Background	ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).
Synonyms	MGC23980; OTTHUMP00000021172; RP11-27J8.2
Note	ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry at 10 µg/ml.
Reference Data

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