MLX interacting protein (MLXIP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-2µg/mL.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.
Formulation	MLXIP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	MLXIP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 20 kDa; Observed: 21 kDa
Gene Name	MLX interacting protein
Database Link	NP_055753 Entrez Gene 22877 Human UniProt ID Q9HAP2
Background	MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).
Synonyms	bHLHe36; KIAA0867; MIR; MondoA
Note	MLXIP antibody can be used for Western blot at 1 - 2 µg/mL.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.