Adipose Triglyceride Lipase (PNPLA2) Mouse Monoclonal Antibody [Clone ID: AT18E6]

Specifications

Product Data
Clone Name	AT18E6
Applications	ELISA, FACS, FC, ICC, ICC/IF, WB
Recommend Dilution	Western blot: 1/1000-1/2000
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human ATGL (30-504aa) purified from E. coli
Specificity	The antibody recognizes PNPLA2 (ATGL).
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Predicted Protein Size	55 kDa
Gene Name	patatin like phospholipase domain containing 2
Database Link	NP_065109 Entrez Gene 57104 Human UniProt ID Q96AD5
Background	Adipose triglyceride lipase (ATGL) is a 504 amino acid protein that is highly expressed in mouse and human adipose tissue. ATGL is catalyzes the initial step in triglyceride hydrolysis in adipocyte lipid droplets and has acylglycerol transacylase activity. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and hormone-sensitive lipase coordinately catabolize stored triglycerides in adipose tissue of mammals.
Synonyms	Adipose triglyceride lipase, Calcium-independent phospholipase A2, Desnutrin IPLA2-zeta, Pigment epithelium-derived factor receptor, TTS2.2, Transport-secretion protein 2, TTS2, ATGL, Patatin-like phospholipase domain-containing protein 2, PNPLA2
Reference Data

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