Laminin 2 alpha (LAMA2) Mouse Monoclonal Antibody [Clone ID: Mer3/22B2]

Specifications

Product Data
Clone Name	Mer3/22B2
Applications	IHC
Recommend Dilution	1:50 - 1:100
Reactivity	Human, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified protein from placenta
Specificity	Reacts strongly with laminin alpha 2 chain of merosin in human and rabbit skeletal muscle. No reaction is observed in muscle sections from mouse, rat, dog, chicken, hamster or pig
Isotype	IgG1
Formulation	Lyophilized tissue culture supernatant containing sodium azide as a preservative.
Reconstitution Method	The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	laminin subunit alpha 2
Database Link	Entrez Gene 3908 Human UniProt ID P24043
Background	The muscle-specific form of laminin, merosin, is composed of three chains: alpha 2, beta 1 and gamma 1. Mutations in the chromosome 6 encoded gene for the laminin alpha 2 chain of merosin are responsible for a form of congenital muscular dystrophy (CMD). Merosin-negative CMD is characterized by a severe clinical phenotype and is associated with white matter changes on brain imaging.
Synonyms	LAMM
Reference Data

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