NAGLU Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGLU
Specificity	Expected reactivity: Cow, Dog, Human, Pig Homology: Cow: 83%; Dog: 92%; Human: 100%; Pig: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	81kDa
Gene Name	N-acetyl-alpha-glucosaminidase
Database Link	NP_000254 Entrez Gene 4669 Human UniProt ID P54802
Background	This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
Synonyms	alpha-N-acetylglucosaminidase; MPS-IIIB; MPS3B; N-acetyl-alpha-glucosaminidase; NAG; UFHSD; UFHSD1
Reference Data

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