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China
GPBAR1 Rabbit Polyclonal Antibody
CNY 4,628.00
Product images
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | WB |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | Expected reactivity: Human, Rat Homology: Human: 100%; Rat: 100% |
| Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Predicted Protein Size | 35kDa |
| Gene Name | G protein-coupled bile acid receptor 1 |
| Database Link | |
| Background | This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. |
| Synonyms | BG37; GPCR; GPCR19; GPR131; hBG37; hGPCR19; M-BAR; MGC40597; TGR5 |
| Reference Data | |
| Protein Families | Druggable Genome |
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