GCLC Rabbit Polyclonal Antibody

CAT#: TA365360

GCLC rabbit polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: Raw264.7,A549,Hepg2 and Jurkat cell
IHC: 25-100
Positive control: Human brain
Predicted cell location: Cytoplasm and Cell membrane
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human GCLC
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C.
Predicted Protein Size 73 kDa
Gene Name glutamate-cysteine ligase catalytic subunit
Background Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Synonyms Gamma-ECS; GCL; GCS; GLCL; GLCLC
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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