CCR6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 20-100 Positive control: Human breast cancer Predicted cell location: Cytoplasm and Cell membrane
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CCR6
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	C-C motif chemokine receptor 6
Database Link	Entrez Gene 1235 Human UniProt ID P51684
Background	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Synonyms	BN-1; CC-CKR-6; CCR-6; CD196; CKR-L3; CKR6; CKRL3; CMKBR6; DCR2; DRY-6; DRY6; GPR-CY4; GPR29; GPRCY4; OTTHUMP00000017618; STRL22
Reference Data

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