KCTD16 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human cerebrum tissue,rat brain tissue and Mouse brain tissue IHC: 25-100 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human KCTD16
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	49 kDa
Gene Name	potassium channel tetramerization domain containing 16
Database Link	Entrez Gene 57528 Human UniProt ID Q68DU8
Background	The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Synonyms	DKFZp781A1155; KIAA1317; MGC138167
Reference Data

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