Bcl2 Binding component 3 (BBC3) Rabbit Polyclonal Antibody

CAT#: TA373942

PUMA Rabbit polyclonal Antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications ICC/IF, IHC, WB
Recommend Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:100
IF,1:50 - 1:100
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human PUMA (NP_001120713.1).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 10kDa/14kDa/20kDa/26kDa
Gene Name BCL2 binding component 3
Background This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Synonyms FLJ42994; JFY-1; JFY1; PUMA
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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