EIF4G1 Rabbit Polyclonal Antibody

CAT#: TA375837

Phospho-EIF4G1-S1108 Rabbit polyclonal Antibody



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CNY 2,900.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB,1:500 - 1:2000
Reactivity Human, Mouse, Rat
Modifications Phospho S1108
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic phosphorylated peptide around S1108 of human EIF4G1 (NP_001181875.1).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 154kDa/158kDa/166kDa/171kDa/175kDa/176kDa
Gene Name eukaryotic translation initiation factor 4 gamma 1
Background The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Synonyms DKFZp686A1451; eIF-4G1; EIF4-gamma; EIF4F; EIF4G; EIF4GI; p220
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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