Kv beta 2 (KCNAB2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	WB,1:500 - 1:2000 IF,1:50 - 1:200
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-40 of human KCNAB2 (NP_003627.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	33kDa/39kDa/41kDa/43kDa/46kDa
Gene Name	potassium voltage-gated channel subfamily A regulatory beta subunit 2
Database Link	UniProt ID Q13303
Background	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Synonyms	AKR6A5; HKvbeta2; HKvbeta2.1; HKvbeta2.2; KCNA2B; KCNK2; KV-BETA-2; MGC117289; OTTHUMP00000000874; OTTHUMP00000000875; OTTHUMP00000000877
Reference Data

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