S Protein Rabbit Polyclonal Antibody

CAT#: TA381935

SARS-CoV-2 Spike Rabbit polyclonal Antibody



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CNY 2,700.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications Dot, ICC/IF, IP, WB
Recommend Dilution ELISA,1:40000-1:160000
WB,1:500 - 1:2000
IF,1:50 - 1:200
IP,1:50 - 1:200
Reactivity SARS-CoV-2
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide of SARS-CoV-2 Spike.
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Gene Name S Protein
Background The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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