Angiopoietin 1 (ANGPT1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1/1000-1/5000
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human Angiopoietin 1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	57kDa
Gene Name	angiopoietin 1
Database Link	Entrez Gene 284 Human UniProt ID Q15389
Background	Swiss-Prot Acc.Q15389.Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
Synonyms	AGP1; AGPT; ANG-1; ANG1; KIAA0003
Reference Data

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