eNOS (NOS3) Mouse Monoclonal Antibody [Clone ID: 2E8-5A5-7B1]

Specifications

Product Data
Clone Name	2E8-5A5-7B1
Applications	WB
Recommend Dilution	WB: 1/500-2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Protein of eNOS
Isotype	IgG1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):130
Gene Name	nitric oxide synthase 3
Database Link	Entrez Gene 4846 Human UniProt ID P29474
Background	Swiss-Prot Acc.P29474.Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Synonyms	cNOS; EC-NOS; ECNOS; eNOS; NOSIII
Reference Data

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