SIRT2 Mouse Monoclonal Antibody [Clone ID: 1D4-H11-H11]

Specifications

Product Data
Clone Name	1D4-H11-H11
Applications	IF, WB
Recommend Dilution	WB: 1/1000 ICC: 1/100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant human SirT2 protein expressed in E.coli.
Isotype	IgG2b
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	43kDa
Gene Name	sirtuin 2
Database Link	Entrez Gene 22933 Human UniProt ID Q8IXJ6
Background	Swiss-Prot Acc.Q8IXJ6.Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.
Synonyms	SIR2; SIR2-like; SIR2L; SIR2L2
Reference Data

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