TRUB2 Rabbit Monoclonal Antibody [Clone ID: R08-5D1]

Specifications

Product Data
Clone Name	R08-5D1
Applications	WB
Recommend Dilution	WB: 1/1000
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human TRUB2
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 37 kDa; Observed MW: 37 kDa
Gene Name	TruB pseudouridine synthase family member 2
Database Link	Entrez Gene 26995 Human UniProt ID O95900
Background	Swiss-Prot Acc.O95900.Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs (PubMed:27974379). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).
Synonyms	CLONE24922; RP11-339B21.1
Reference Data

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