Cd28 Rabbit Monoclonal Antibody [Clone ID: JJ316]

Specifications

Product Data
Clone Name	JJ316
Applications	FC, IF, IHC
Reactivity	Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
Specificity	Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo. This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.
Isotype	IgG, kappa
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	Cd28 molecule
Database Link	Entrez Gene 25660 Rat UniProt ID P31042
Synonyms	MGC138290; Tp44
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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