CD38 Rabbit Monoclonal Antibody [Clone ID: AT13/5]

Specifications

Product Data
Clone Name	AT13/5
Applications	FC
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Namalwa cells emulsified in CFA.
Specificity	Binds specifically to human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. This antibody competes with clone HB7 (Ab00128) (Ellis 1995) which has been shon to bind to an epitope between amino acids 273-285). The antibody binds to CD38, a glycoportein on the surface of various immune cells that catalyzes the hydrolysis of cyclic ADP-ribose to NAD+ and ADP-ribose.
Isotype	IgG, kappa
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD38 molecule
Database Link	Entrez Gene 952 Human UniProt ID P28907
Synonyms	T10
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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