TAPA1 (CD81) Rabbit Monoclonal Antibody [Clone ID: 1D6]

Specifications

Product Data
Clone Name	1D6
Applications	ELISA, FC, IF, IHC, IP, WB
Reactivity	Human, Chimpanzee, Goat, Sheep
Host	Rabbit
Clonality	Monoclonal
Immunogen	This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.
Specificity	This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets. This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).
Isotype	IgG, kappa
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD81 molecule
Database Link	Entrez Gene 975 Human UniProt ID P60033
Synonyms	S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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