Ccr9 Rabbit Monoclonal Antibody [Clone ID: 9B1]

Specifications

Product Data
Clone Name	9B1
Applications	FC, Neutralize
Reactivity	Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
Specificity	9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells. This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	chemokine (C-C motif) receptor 9
Database Link	Entrez Gene 12769 Mouse UniProt ID Q9WUT7
Synonyms	CC-CKR-9; CCR-9; CDw199; CMKBR9; GPR-9-6; GPR28
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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