ZKSCAN3 Rabbit Polyclonal Antibody
CAT#: TA386801
ZKSCAN3 Rabbit polyclonal antibody
Size: 50 ug
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CNY 1999.00
CNY 3280.00
CNY 300.00
CNY 1430.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Reactivity | Mouse, Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant Human Zinc finger protein with KRAB and SCAN domains 3 protein (8-275AA) |
Isotype | IgG |
Formulation | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Concentration | lot specific |
Purification | >95%, Protein G purified |
Conjugation | Unconjugated |
Storage Condition | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Database Link | |
Background | Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
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