ERCC2 Rabbit Polyclonal Antibody

CAT#: TA387469

ERCC2 Rabbit polyclonal antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration lot specific
Purification Antigen Affinity Purified
Conjugation Unconjugated
Storage Condition Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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